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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2c46fceb7ff778fa389dd92f79f6b8b2e159e3ad14eb1a6507b90fe8fdad462' 
  AND token = 'VDXSSE5jZ/n877PdXbAEXs9yaRtu24dnfw2a7ibjOQc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}