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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7e55c8c12a2154a2213f98d7625f87b3732cc6a4d974af5422f8f4902a5df4' 
  AND token = 'j39DVLNZuuzr81wisiqNPcqtF4TcDiOjRvy1Y5dxPZc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}