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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8899e81c5395a74128b49b33457c0ae2b6dd576c678e884cad51a186c8843513' 
  AND token = 'FNp8BDZCp4VtLksyRYRDdu9e5Af7ElvMTBs15dVdUc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}