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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '07912a7338b6abc7e91606d3ad7bbe0a6e1af381693e01a84ece0e0f719e4486' 
  AND token = 'S02bsIZq8ePWvsuC5dAqhE2z4GKHRJIWCBzZWXWqEXY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}