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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18b05b799a860e5f4374e84975b3b9f45e13d60988bc6edc3e96122bbc3b78c3' 
  AND token = 'AFC1FGWz/XoEUe0+WeWcrWCeJZeSwTIeDW9xAXc8dr4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}