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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21cedcfefd53a87a98ef2169a4cf4b4f4316f3569d31db9b1a19c6cf31544528' 
  AND token = 'ZXJy1CEHkir6p2S/7prDmInG8a5rWGefZRJk8j5BYn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}