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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f6a5da69fff8c7f49578d46ed2c9e33434c4219b25bc370b5906017133abad69' 
  AND token = 'E4t9GsYnuBGlKbadpx0/YssAT9r3JwUfKq95Mcum+fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}