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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '015040dbdc77fc5fccf0e99989fb723cb31334c07693c2ba203d572ee087d0b6' 
  AND token = 'tppVSQm/9fzu9G5TYUNJxvEbz+bn+3a7ZgO5lyEQaDY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}