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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8190253f59eb84088b287ed56a9a12deb09abafeec2a69271f15c29065be6042' 
  AND token = '1Db9pfoXT6RQSON/1S74wDLRFmD5rF8VnI4lC5inaBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}