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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f5b396b6c82bf4a5c03a040c321f6dae4b6f8272a15750876460490ce292285c' 
  AND token = 'FcVdR3UyEcfJ3CWq21Vd5fian0twp3pwdlL4ZTyZV0E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}