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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f73d44cf7bf96c9891243a3307d59241991dd494782a9a76009277eb75fdb241' 
  AND token = 'Q5v2KWmLFqBAhqSx8s8bNz8hudfH+k72D8DKdK0Hl0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}