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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33fcdd5d56199fe49892ed8c7dfc0469ad180a9c6bcca2265cde26aa553ac436' 
  AND token = 'kCUwh+NLnoxmNem0N99Fvem758pg3tMNrsCsOFgRMuU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}