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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2491e31195ee25f383babed4e6ace4b05b809eeaa7b18118be2df1f4e7d6da44' 
  AND token = 'DqEMViaTkVBwyF6ERDQpnvhYwyuEfPkWaR9P4ILi/Y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}