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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d7f8354d48937801c700c8d7e007e053dbd586daf6f8387aee2035658c6c3eb' 
  AND token = 'iE3JaPCRjY5kFzldGhAEZDTUAaWXGQlc7Vuby+yUcn0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}