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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12901c56ff166f2fa148b94e83cd51111f945469f0ab15cb8e6263abf14e18d3' 
  AND token = '/rADGOeCgbhSXs6kDgw+OSAtjGvyfXTZU+2T+N5sGeY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}