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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c81ca1b22d18721c3e450122965f9604d45bb1ab50d2f7ff595cd4e479e2ce85' 
  AND token = 'Od5Ibjd7jx5j9LDuJfqpbMrWf2yzzg4nIWB2fPxVU8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}