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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15ae4a9c9bea2f01d91307e115db4474a76ee22ab0674cf92d7cb35af4b76946' 
  AND token = '/aYcQ3CgdbjF0UdPRQeMBhimMQnyFUgUXCJlRQAAMFI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}