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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a1aa18aa8c5f254440662a4a52e8e79a3394c2b908c39fc8fdc733938f50966' 
  AND token = '6mfrKc2XLUo7LcaTkfOSZ1ddB9Dxsv+6dN768I6/+d8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}