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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3dd811087e6764c9ac07b3d679c5803a0635d979a30a955de74a3f7bff8b4387' 
  AND token = 'Cw8a+spMZ5K1KUjkxMzCTe8NMFtXbq6DjPTtoER8cMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}