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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f954b63cd0a5a2be42fed0bb73863cfce80067632a85efc14d0ad2347d0f3b7' 
  AND token = 'og6pMM3LSD/jTY5k6m65Yaw9HNPF5LPbvmjGF/Yr+qY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}