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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d4d515f3c156275ba7eeb699c36f7e7e2b05390e9d008c241015280017b9084' 
  AND token = '0Y9JE+VVctUoK/GkmNalL1vElUlYqM1h9fsx3Je6um8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}