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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a754208746a9775b9cafd48e7dcef1cf1034a2a50240afc0b37cabc51f82b57' 
  AND token = 'pRgpLeUtAYHGTRzSEl4F+vk7G+QGaig+XM1pGCD3vx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}