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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ee8f18de4783fa08cbed533b7e3b7deca91fe814bbafe29dde60ad1f02c86177' 
  AND token = 'FrUUTxgszGuIxGMawKj7i2mRPp5pBgg5xE4aO6xUM8w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}