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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ad799b11f4e61bf1e0c27b122c1e870066d3d8155457be05d29ffdcc9b187ae' 
  AND token = 'JP50GQk4G+ePMxaQp6tybmWLmoFFrT9YbUQm03uQRT8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}