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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '340484c74a804a0dc1313bea7e8b6135b745ec0d8f2c5975ba39599cce863802' 
  AND token = '8wJD80IV2VyM9Ph/9lIQLyaKE2Mpiu+nfzvPJbbMbYM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}