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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3345f2b4f1aab275dc514a22b079343cdcf76ed618a636bc36519b4c0f40e111' 
  AND token = 'cV1pvZlt3cOixn4I9MfGv0BIkVvC0xmSJ5X+3bOWqUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}