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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a43cb0e415ceba058603d741c35c0b18b8152d9ee50e03f8eab564e98f1429d' 
  AND token = '5XLvLtvM6aN4QY/HuS+w4dT84Hai98KrrsXv/jxZah8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}