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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61922d5b4baa0e317aee8a6b598e04f800d1c210d25329e94e97447d5dd62a62' 
  AND token = '1qEU/MidL/+e5u4ass8MLXK4pS290Lpgt+c25iSlKms=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}