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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc603cbb44d6a8666a23f856fba862dd0f94efb21e4bfba731e91e488a2cbbc' 
  AND token = 'FYI+8KmCLLHoq+mJyWxm1ak/yvmiDwZQM22KOb5c6Qc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}