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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f376f610038eb4e5c01d8b2e27cd274834afe8fe6cfa8de0e8651697bf9a4e1' 
  AND token = 'q2pEd8D6KNbEFjsOyVNwK79qc2iP+Ts891EbfarGlrY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}