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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e03c428c61085c283e8bff52501e09e4b4c43ba0a25d6413c63e8b056d5fa020' 
  AND token = 'bUttPvBEJrPZtpxQ4RsMIxbwqGO6FT7yWDQF1GP7EdQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}