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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '072535cb9a922cee66d0de563b529ca2f1064b57e2174eef8545cde572c12887' 
  AND token = 'TXu4xDMHb/GzWA4d00YhH+LIlmi1QtqcwmBk4PCo7w0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}