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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a588f94992c269593e79f16b6bcb12e967e4eb6465ede4ec6bffd6d6f6c2f840' 
  AND token = 'XAr1Ny9i7Gy62yFOLXdhz4JrHbH7TsHhfO1ZGikne8M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}