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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dc4010729f27670393909dcb10e8e3f0e022f7a04dee486c823a7eca90fe31f4' 
  AND token = 'efw8L2nT7LVKKvSYnr6BphWVP0zIMF0E5tjrd3cfbLY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}