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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '842e2cd48ca01b47ddfba9f8aba3ad7314f934f373cc74810915e4c85d646831' 
  AND token = '/txCGm2mP1DpypgwY3sTkbrryI0fTzbQCzzYNvEa/y8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}