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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efce9b5d97d3d24170e3880299fa764b5c3d3a45fcd6789da3bd3e93f9857cb4' 
  AND token = 'z27iE9r4Fbh5bDBLym/sM8udD8vN8iUhgVt38UuM1A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}