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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9e51b43923f3a85d327b665710c774b03539dce42a2a6c046aaf2c1423078d8b' 
  AND token = 'cDjGiUWnrgAl5UuZBvc3dXAnEeGZV2fDnFDt7J0/YL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}