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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6cad77cd6b812e20ccf4449917c3b259a06446814c2c0836011306abe67d64f5' 
  AND token = 'O0VH2r8SO+xR8xFjrNHwo+aoGCQUVnHBMaxkvkvW0Eg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}