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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '461e92ed938a5984dea11de36f71775f6a4f238530bf26e0bb3fa5f4024b9815' 
  AND token = 'bWYNad2r8ohMnAo0BjdjVrm3biNaq/ZP0PR2ejnPp6Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}