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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3bc63eb1506932fbea5d0243926495e76b2d2675afc4bdc2f61c59c48e53f0c8' 
  AND token = 'drOL3Wt/TPpqYsDZ736737W/ASUeto6/P4vkKBddcPU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}