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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0da6e188d6e16ad0aedfd1cd03c216ec3bad030ec767ce014bcf0cab42ea7872' 
  AND token = 'rTN/1zA8DSfVHizPRZb+DEHkGr+OFV2ZoUiVk2k0NpM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00040

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}