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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c38448ec3c63ab9638a391f42f606e7e0908b8afaad18ed8721bc67321e1b78f' 
  AND token = 'qgQnXSDpXg0BhA38KaWmzziIGPAwjwzQ8zrFv6HB0g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}