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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd99454f0b53b408a799db1c6be508bf417dc16b52ebc1727b105a1815b890b8b' 
  AND token = 'Uza34CXRvyU+AzKrTH3lNBBMNVyp0DWZdRom80xRPVY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}