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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf8c5105320f327a7333b070426858f6c214a71945a91b582746ac8a513f4349' 
  AND token = 'XHseUjvCmQBhqQJGCIAW2+k0tsDPTHiP1tPA52iPwMk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}