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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9411346e71ca6d2051955c33f8799f4447c9c77ef73dbeea653322a2abce1c6f' 
  AND token = 'iC/tVCYGD8MphwiP/a8CP6OQK4pVpD/xaE+EprcQ2k0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}