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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b5a721c73a66cd7a3e151b042ca699080eefeaa7fd24830af0c4f5b2cadcc1d5' 
  AND token = 'VUO5DzDMqHyepw10zWt3FWu2wB6vB1hDPk5/tZdEDGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}