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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5837e875701be13f9acf1da4b5adbdd5c2f9823d0c0ce72bdd03c64c054e5ac6' 
  AND token = 'zGFvXixbZ74DcJ4KZ93MF5zztlFFb+/1yIlXj0yY53k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}