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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ac45683473d7c1e513d284981f6ca855d8b747e8c44db87639d8081a2baacdd' 
  AND token = 'SB4u/M1n8A/1RbDX1/TG3+8lfye7bYrz25d7rOpUOyw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}