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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b045b74645063c90e3bdfe49193ff3c3c5d4e866eab4fe03e4abc844e48d8a1d' 
  AND token = 'XUigPp3HtuYd7RdqJ6vBO0rGikUtCHbCuPi+7dAJAZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}