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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd189f2a2b9376ccba0adc8396d16af4d9d26d82177e1293a02971ff028eba2fc' 
  AND token = 'dlFHbFa2Kk/Y1ENi7BZKjR/WDaD/NU5ulxUFmcSOQKw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}